26^th Global Obesity Meeting

Genetics of Obesity

Genetics, contributing 40-70% to obesity risk, influence susceptibility alongside lifestyle factors like diet and activity. Specific genes affect metabolism, appetite, and fat storage. Rare mutations lead to severe early-onset obesity, while common variants collectively impact weight gain. Variations affect hormones like leptin and metabolism. Environmental changes, coupled with genes, drive obesity's rise. Precision medicine aims for personalized strategies, but lifestyle remains vital. Behavioral factors, like habits and stress management, interact with genetics. Although genetics are a part, lifestyle, environment, and health are equally important. Healthcare experts, including genetic counselors, guide holistic obesity management.